The WIBOsafe aseptic isolators work with laminar air flow with a flow velocity of 0.45 m/s ± 20%. Pre-filtered fresh air is drawn in from the surrounding area and fed into the work area from above via flat HEPA filters. Extraction takes place via the work surface. For aseptic-toxic applications, a bag-in/bag-out (BIBO) filter system can be integrated into the exhaust air duct. Double containment flaps ensure that the air ducts remain gas-tight when not in use.

The laminar air flow in the material locks takes place with supply and exhaust air via upstream and downstream HEPA filters H14. The doors are magnetically locked against each other and monitored. Each time the door is opened, there is a fixed flushing time with a > 100-fold air exchange rate, which ensures that airborne particles in the airlock are discharged quickly.

The controlled supply air in the isolator chamber generates a defined constant flow without turbulence. WIBOsafe isolators thus meet the requirements of clean room class A according to EU GMP and ISO class 5 in accordance with ISO 14644-1.

Depending on requirements, the air flow system can also be converted to negative pressure.